Glutamine Synthetase in the Normal and Dystrophic Mouse Retina

Biochemical and molecular analysis of glutamine synthetase gene in brassica napus L.

Steroid control of the normal development of glutamine synthetase in the embryonic chick retina.

Glutamine synthetase (GS) activity in the neural retina of the chick embryo is inducible with corticosteroids (Moscona & Piddington, 1966; Piddington, 1967; Moscona, Saenz & Moscona, 1967; Moscona, Moscona & Saenz, 1968; Alescio & Moscona, 1969). Striking increases in retinal GS activity can be elicited with hydrocortisone in ovo days in advance of the normal rapid rise of this enzyme (Piddingt...

A radiochemical assay for glutamine synthetase, and activity of the enzyme in rat tissues.

1. A radiochemical assay for glutamine synthetase has been developed in which an ATP-regenerating system is incorporated to prevent accumulation of inhibitory amounts of ADP. It is particularly suitable for assay of the enzyme in crude tissue extracts containing high adenosine triphosphatase activity. 2. A survey of the distribution of the enzyme in tissues from normal male rats showed that act...

Control of glutamine synthetase synthesis in the embryonic chick neural retina. A caution in the use of actinomycin D.

The cortisol induction of the enzyme glutamine synthetase (EC 6.4.1.2) in the embryonic chick neural retina is controlled initially at the transcriptional level, as previously demonstrated by the unique appearance of a 15 S RNA species which codes for a single and identical polypeptide chain of glutamine synthetase. This is found only on polyribosomes of cortisol-treated retinas. Recent experim...

Control of Glutamine Synthetase Synthesis in the Embryonic Chick Neural Retina

The cortisol induction of the enzyme glutamine synthetase (EC 6.4.1.2) in the embryonic chick neural retina is controlled initially at the transcriptional level, as previously demonstrated by the unique appearance of a 15 S RNA species which codes for a single and identical polypeptide chain of glutamine synthetase. This is found only on polyribosomes of cortisol-treated retinas. Recent experim...